The Microhemodynamics Laboratory
in the Department of Bioengineering at UCSD is
led by Professor Marcos Intaglietta. The main research
objective is to understand how underlying mechanistic
and functional changes of the microcirculation during
normal and pathological states can ultimately predict
The maintenance of homeostasis in
an organism can be traced to the events at the level
of microscopic blood vessels, the site of vital transport
and gas exchange. This network of microvessels ranging
in diameter from 5 to 150 µm exist in every
tissue and organ of the body.
The development of non-invasive instrumentation
to investigate the microcirculation in vivo
remains one of the cornerstones of this laboratory.
Much of the instrumentation and related analysis methods
being used were developed in this laboratory and have
found acceptance in laboratories throughout the world.
The research is hypothesis driven
and results have clinical applications to the development
of therapeutic agents and techniques. The laboratory
enjoys valuable and close collaboration with eminent